Chromatography- Best Choice For Separating Fine Chemicals

Chromatography – An Introduction

Chromatography is a separation and purification technique mainly used to separate individual components of a mixture so that they can be separately analyzed and researched upon. Chromatography consists of a stationary or solid phase and a mobile or liquid phase. The most commonly used types of Chromatography are Column Chromatography, Thin-Layer Chromatography and Flash Chromatography. All these chromatography methods are designed to cater to different needs of various customers. 

The main applications of Chromatography are in the separation of fine chemicals, differentiation and purification of antibiotics, purification of DNA samples and biomarkers. Read on to find out how chromatography makes the separation process of different fine chemicals a lot more easier.

Chromatography in Separation of Fine Chemicals

Chromatography is very useful in the separation of fine chemicals as this process easily helps segregate the different fine chemicals that make up any mixture. Often people find it very difficult to separate fine chemicals when they are present in small quantities. This is where the process of chromatography proves to be useful. It is the best method available in which small quantities of fine chemical mixture can be separated without any difficulty. 

Another advantage of using Chromatography to separate fine chemicals is that it can be done in very less time. If one opts for this type of purification process, one can be guaranteed of accurate separation of components in the minimum time possible. This can be achieved with flash chromatography. 

One can also make use of the chromatography process to separate fine chemicals, which are very similar in physical appearances and have an almost identical chemical composition. Separating such chemicals becomes very difficult and this is where the role of chromatography becomes important. These fine chemicals cannot be separated by the usual modes of separation.  

The use of Silica Gel Column Chromatography and Flash Chromatography in the separation of fine chemicals has other uses also. It brings down the level of solid consumption, increases the production and purification rate and results in lesser dilution of the product streams. The movement of the mixture through the stationary phase and mobile phase will lead to accurate separation of the fine chemicals as they settle down at different levels based on their solubility.